Journal of Chemical and Pharmaceutical Research

ABSTRACT In the present investigation, a series of uracil formazans (5a-r) were synthesized by condensation of schiff base (4a-c) and diazonium salt of various substituted aromaticamines. The intermediate schiff base (4a-c) was itself synthesized by condensation of (6-hydrazino-3-methyl uracil) with various aromatic aldehydes (3a-c). The structures of the compounds have been confirmed by elemental analysis and spectral analysis. Newly synthesized compounds were screened for their antimicrobial activities.

Cu(II), Ni(II), Mn(II) and Co(II) complexes were synthesized with bis(salicylaldehyde)malonyldihydrazone a tetradentate ligand (L) and characterized by elemental analysis, molar conductance measurements, magnetic susceptibility, IR, electronic and EPR spectral studies. Metal(II) salts react with Schiff base ligand in 1:1 molar ratio. The ligand and its complexes are stable at room temperature and all of them are nonhygroscopic also. The elemental analysis for carbon, hydrogen and nitrogen were performed by micro analytical methods. Apart from this, the geometry of the newly synthesized compounds has been explained based on their elemental analysis, molar conductivity and spectral data. The molar conductance measurements of all the complexes in DMF solution correspond to electrolytic nature for the complexes except Mn(II) complexes. PDF