Solid phase extraction of copper, cadmium and lead in environmental samples FAAS using activated carbon modified with 5-(4-dimethyl aminobenzyledeneamino)-2-hydroxy benzoic acid

Sensitive and selective preconcentration procedure was developed for the determination of trace Cu(II), Cd(II) and Pb(II) ions in environmental samples. 5(4-dimethyl aminobezyledeneamino) 2-hydroxy benzoicacid modified with activated carbon was prepared and used as new solid phase extractor. Adsorbed metal ions were eluted with 10ml of 3N HNO3 at a flow rate of 2 ml/min. The concentration of metal ion determined by flame atomic absorption spectrometry (FAAS). Different factors including pH of the sample solutions, effect of sample volume, the amount of modified activated carbon, type and volume of eluent were examined. The proposed method was applied to the determination of metal ions in water samples and soil samples with satisfactory results (recoveries range from 96 to 99%).

PDF

Comments

Post a Comment

Popular posts from this blog

Quantitative analysis of civetone and normuscone in secretion from Viverricula indica and in aromatic remedies by gas chromatography-mass spectrometry

Image
ABSTRACT : The quantitation of civetone and normuscone in small Indian civet (Viverricula indica Desmarest) secretion cultivated in Thailand was analyzed by gas chromatography- mass spectrometry (GC-MS). Three main chemical constituents of small Indian civet secretion were civetone, dihydrocivetone and normuscone. The contents of chemical constituents were different between male and female secretion. Civetone (23.6 ± 1.5 µg/mg of secretion) was a major chemical constituent in the female secretion while normuscone (52.1 ± 5.9 µg/mg of secretion) was a major in the male secretion. Both civetone and normuscone were found in civet fur but not in the feces. Aromatic remedies which claimed to use the small Indian civet secretion as an ingredient showed both civetone and normuscone. Linearity range of civetone was 0-50 µg/ml with a correlation coefficient of 0.9717, and of normuscone was 0-80 µg/ml with a correlation coefficient of 0.9965. The average recoveries were 97.3-98.0% in sec...
Read more

Antimicrobial activity of aqueous, ethanolic, methanolic, cyclohexanic extracts and essential oil of Nigella sativa seeds

Image
  ABSTRACT : Most of the bacterial pathogens are resistant to existing synthetic antibacterial agents demanding an increasing effort to seek effective phytochemicals as antibacterial agents against such pathogens. Nigella sativa L. (black cumin) seeds play an important role in folk medicine and some of its major constituents are reported to be pharmacologically active. In this present work, Nigellasativa seed extracts were obtained using maceration extraction by various solvents (water, ethanol, methanol, and cyclohexan). The antibacterial and antifungal effects of different extracts and essential oil of seeds were investigated by the agar diffusion method against two gram positive (Bacillus subtilis CIP52.62 ,Staphylococcus aureus CIP4.83) and three gram negative strains of bacteria (Escherichia coli CIP53.126 ,Pseudomonas aeroginosa CIP82.118, Salmonella abony CIP80.39) and one strain of fungi (Candida albicans CIP48.72). All the extracts and essential oil showed varying d...
Read more

A Validated specific Stability-indicating RP-HPLC method for Aripiprazole and its related substances

Image
ABSTRACT : A validated specific stability indicating reversed-phase liquid chromatographic method was developed for the quantitative determination of Aripiprazole and its related substances in bulk samples, pharmaceutical dosage forms in presence of degradation products. Forced degradation studies were performed on bulk sample of Aripiprazole as per ICH prescribed stress conditions using acid, base, oxidative, thermal stress and photolytic degradation to show the stability indicating power of the method. Significant degradation was observed during basic stress and no degradation was observed in other stress conditions. The chromatographic method was optimized using the samples generated from forced degradation studies and the impurity spiked with Aripiprazole. Good resolution between the peaks corresponds to impuritiy-1, degradation products from the analyte were achieved on YMC PACK C18 column using the mobile phase consists a mixture of Sodium dihydrogen Orthophosphate dehydra...
Read more