Synthesis and study of antibacterial and antifungal activity of novel 2-(5-substituted methylamino-1,3,4-thiadiazol-2yl)phenols
A new series of Anti bacterial and Antifungal agents with
2-(5-amino-1, 3, 4-thiadiazol-2-yl) phenol as the central scaffold unit has
been synthesized. The newly synthesized compounds were characterized by IR and
1HNMR spectral methods. The compounds were screened for antibacterial activity
against pathogenic microbes Bacillus subtilus, Staphylococcus aureus, E.coli,
in comparison with the reference drug Ampicillin, Ciprofloxacin and Doxycycline
and antifungal activity against Candida albicans and comparable to that of
Fluconazole as a reference drug and in this investigation the significant level
of activity was illustrated.
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