Phytochemical studies on Leucas aspera
ABSTRACT:
Drugs from the plants are easily available, less expensive, safe, and efficient and rarely have side effects. The alkaloids, tannins, flavonoids and phenol compounds play a major role in preventing a number of chronic diseases by a definite physiological action on the human body like anti-inflammatory, anti-thrombotic, anti-oxidant, hepatoprotective and anticarcinogenic activities.Leucas aspera (Family:Lamiaceae) commonly known as 'Thumbai' is one such medicinal plant which is being used traditionally as an antipyretic and insecticide. Parts of the plant is also being used for many disorders like rheumatism, psoriasis and chronic skin eruptions.The aim of the present study was to evaluate the invitro phytochemical analysis on aqueous ethanolic extract of whole plant of Leucas aspera. Phytochemical screening was carried out for chloroform,aqueous ethanol and water as per the standard methods. Plant contains sterols, alkaloids, flavonoids,galactose, oleanolic acid, ursolic acid and Beta-sitosterol . Aerial parts contain alpha -sitosterol, beta-sitosterol. The plant extracts were subjected to quantification of phytoconstituents such as total phenolic content and total antioxidant capacity by invitro methods. Preliminary phytochemical screening of the extract(chloroform and aqueous ethanol) revealed the presence of various bioactive components which include alkaloids, flavonoids, steroids, cardiacglycosides, saponins and tannins. The total antioxidant capacity and total phenolic contents of ethanol extract were found to be 190.00± 7.95 mg/g and 15.36 ± 0.512 GAE/g dry weight of extract respectively. From invitro studies it can be concluded that ethanol soluble fractions of L.aspera showed good antioxidant activity and thus scientifically proves the use of entire plant in traditional medicine for various ailments.
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Drugs from the plants are easily available, less expensive, safe, and efficient and rarely have side effects. The alkaloids, tannins, flavonoids and phenol compounds play a major role in preventing a number of chronic diseases by a definite physiological action on the human body like anti-inflammatory, anti-thrombotic, anti-oxidant, hepatoprotective and anticarcinogenic activities.Leucas aspera (Family:Lamiaceae) commonly known as 'Thumbai' is one such medicinal plant which is being used traditionally as an antipyretic and insecticide. Parts of the plant is also being used for many disorders like rheumatism, psoriasis and chronic skin eruptions.The aim of the present study was to evaluate the invitro phytochemical analysis on aqueous ethanolic extract of whole plant of Leucas aspera. Phytochemical screening was carried out for chloroform,aqueous ethanol and water as per the standard methods. Plant contains sterols, alkaloids, flavonoids,galactose, oleanolic acid, ursolic acid and Beta-sitosterol . Aerial parts contain alpha -sitosterol, beta-sitosterol. The plant extracts were subjected to quantification of phytoconstituents such as total phenolic content and total antioxidant capacity by invitro methods. Preliminary phytochemical screening of the extract(chloroform and aqueous ethanol) revealed the presence of various bioactive components which include alkaloids, flavonoids, steroids, cardiacglycosides, saponins and tannins. The total antioxidant capacity and total phenolic contents of ethanol extract were found to be 190.00± 7.95 mg/g and 15.36 ± 0.512 GAE/g dry weight of extract respectively. From invitro studies it can be concluded that ethanol soluble fractions of L.aspera showed good antioxidant activity and thus scientifically proves the use of entire plant in traditional medicine for various ailments.
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