Antimicrobial activity of Polycarpaea corymbosa Lam. (Caryophyllaceae) against human pathogens
ABSTRACT:
Polycarpaea corymbosa are widely used traditional medicinal
plant to treat various ailments. The antimicrobial potential of Polycarpaea
corymbosa against human pathogenic microorganisms (fifteen bacteria and six
fungus) ware investigated. Antimicrobial activity of various plants extracts
was compared with commercially available antibiotics. The antimicrobial
potential of the above plant extracts was seen against the test organism using
disc diffusion method. The phytochemical prospection of the dried aerial and
root extracts showed the presence of different classes of secondary
metabolites, as phenols, flavonoid, alkaloids and tannins that have
demonstrated antimicrobial action. Acetone and methanolic extracts showed
considerably good antibacterial activity against all bacteria and fungi. This
study shed the light on the ability of extracts from the plant to combat
pathogens which will help as natural antimicrobial agents as well as can be
used in pharmaceutical and food preservation systems.
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