Antimicrobial activity of methanolic extracts of Azadirachta indica, Rosmarinus officinalis and Lagenaria siceraria leaves on some important pathogenic organisms
ABSTRACT:
In India, a large
number of medicinal plants occur in the wild state. Presences of the phytochemical
constituents such as alkaloids, flavonoids, tannin, and phenolics compounds
have been reported to be important compounds in many other medicinal plants.
These compounds exhibit diverse actions such antibacterial, analgesic,
antifungal .antidiabetic and antioxidant etc. The main objective of this work
was to study the antibacterial activity of methanolic extracts of Neem
(Azadirachta indica), Rosemary (Rosmarinus officinalis) and Bottle guard
(Lagenaria siceraria) leaves on some important Pathogenic organisms. The
methanolic extracts of leaves of Neem, Rosemary and Bottle guard were evaluated
for its antibacterial activity against staphylococcus aureus pseudomonas
aeruginosa. , E.coli and Klebsiella using Agar well diffusion technique. The
methanolic extracts of leaves of Neem, Rosemary and Bottle guard (MEAIL, MERML
and MELSL) showed zones of inhibition on agar plates. The methanol leaf
extracts of Neem leaves, Rosemary leaves and Bottle guard fruit showed
significant antibacterial activity against Escherichia coli, Pseudomonas,
Staphylococcus aureus and Klebsiella. Extensive studies may yield cost
effective antibiotics for future.
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