Research on the law of hydraulic fracture and natural fracture intersecting extension in the heterogeneous fractured reservoir
ABSTRACT:
Selective molecularly imprinted polymers (MIPs) for solid-phase
extraction and determination of glipizide have been designed and prepared. MIPs
were synthesized with acrylamide as the functional monomer and
ethyleneglycoldimethacrylate as the cross-linker in chloroform as a porogenic
solvent by using bulk polymerization method. MIPs are able to bind 100%
glipizide in chloroform by using a batch method compared to a non-imprinted
one. By using Fourier Transform Infra Red, it was found that hydrogen bonding
occurred between the carbonyl group of acrylamide and the proton donor of
template. These results find the opportunity for this MIP to be used as an
alternative of the pretreatment method before determination of glipizide by
using glibenclamide as a pseudotemplate.
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