Synthesis and evaluation of some new substituted 1, 4-dihydro pyridine derivatives and their anticonvulsant activity


Abstract
 
A series of substituted 1, 4-Dihydropyridine derivatives were synthesized and the structures of these compounds were established on the basis of spectral and elemental analysis. All the compounds were evaluated for anti convulsant activity by Maximal Electroshock Induced convulsions in Rats, PTZ induced convulsions in Rats, and Strychnine induced Convulsions in Rats methods. Compounds A1,A2,A3,A4,B1,B2,B3,B4have been found to exhibit anti convulsant activity

For more info:http://www.jocpr.com/articles/synthesis-and-evaluation-of-some-new-substituted-14dihydro-pyridine-derivatives-and-their-anticonvulsant-activity.pdf

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