Synthesis and study of antibacterial and antifungal activity of novel 2-(5-substituted methylamino-1,3,4-thiadiazol-2yl)p henols


Abstract 

A new series of Anti bacterial and Anti fungal agents with 2-(5-amino-1, 3, 4-thiadiazol-2-yl) phenol as the central scaffold unit has been synthesized. The newly synthesized compounds were characterized by IR and 1HNMR spectral methods. The compounds were screened for antibacterial activity against pathogenic microbes Bacillus subtitles, Staphylococcus aureus, E.coli, in comparison with the reference drug Ampicillin, Ciprofloxacin and Doxycycline and anti fungal activity against Candida Albanians and comparable to that of Fluconazole as a reference drug and in this investigation the significant level of activity was illustrated

For  more info:http://www.jocpr.com/articles/synthesis-and-study-of-antibacterial-and-antifungal-activity-of-novel-25substituted-methylamino134thiadiazol2ylphenols.pdf

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