Synthesis, characterization and bioactivities of Ni (II) and Co(II) complexes of benzyloxybenzaldehydethiosemicarbazone


Abstract 

Ni(II)and Co(II) complexes of benzyloxybenzaldehydethiosemicarbazone(L) were prepared and characterized by their physical, spectral and analytical data. The newly synthesized metal complexes have a composition of [M(L)2X2], where M= Co(II) or Ni(II) and X= Cl. The electronic spectral studies show an octahedral geometry around Ni(II) and Co(II) complexes. The IR spectral data suggest the involvement of sulphurand azomethane nitrogen in coordination with the central metal ion. In order to evaluate the biological activity of the ligand and its metal, complexes have been screened for their antibacterial and antifungal activity against bacterial species like – B.subtilis andS.aureus(Gram-positive bacteria) and E. coli, P. aeruginosa and P. vulgaris (Gram-negative bacteria)and also fungal species like- Microsporumgypseum, Teloschistes villous, Aspergillus fumigates and Candida albicans
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