Quantitative structure activity relationship analys is of a series of antibacterial 3-bromo-4-(1- H -3-indolyl)-2, 5-dihydro-1 H -2, 5- pyrroledione derivatives

Abstract 

The use of quantitative structure–activity relationships, since its advent, has become increasingly helpful in understanding many aspects of biochemical interactions in drug research. This approach was utilized to explain the relationship of structure with biological activity of antibacterial. For the development of new fungicides against, the quantitative structural–activity relationship (QSAR) analyses for fungicidal activities of Pyrroledione  Derivatives were carried out using multiple linear regression (MLR) Quantitative structure–activity relationship (QSAR) analysis was performed on a series of 3-Bromo-4-(1-H-3-Indolyl)-2, 5-Dihydro-1H-2, 5- Pyrroledione Derivatives.