The assessment of etiology in with end – stage renal disease adult hemodialysis patients and blood serum albumin levels


ABSTRACT
Hemodialysis is a commonly used treatment for renal failure when a kidney has lost its ability to regulate fluids, electrolytes, acid/base balance and toxin removal from the blood. It helps the kidneys to excrete wastes and maintains the electrolyte balance in approximately 90% of end – stage renal disease (ESRD) patients. Albumin consists of one polypeptide chain of 585 amino acids and contains 17 disulfide bonds. Hypoalbuminemia is associated with mortality in patients with ESRD and maintaining optimum albumin levels iscrutial in on hemodialysis (HD).

Comments

Post a Comment

Popular posts from this blog

Synthesis of Atenolol Impurities

Image
ABSTRACT: The aim of this research was to synthesis impurities of Atenolol viz. 2-(4-Hydroxy phenyl acetamide(Impurity A) , 2- [4-[[(2RS)oxiran-2-yl]methoxy]phenyl] acetamide (Impurity C) and 2-[4-[(2RS)-3-chloro-2-hydroxypropxy] phenyl]acetamide (Impurity D ) by very conventional method. Further details Home page URL:   http://www.jocpr.com/ For more details PDF Link :    http://www.jocpr.com/articles/synthesis-of-atenolol-impurities.pdf
Read more

Phytochemical investigation of the roots ofGrewia microcosLinn.

Image
ABSTRACT: The present study reports the phytochemical investigation of the roots of Grewia microcos linn. Seven Phytoconstituents have been reported namely 9,12- octadecadienoic acid; Ursolic acid; Stigmasterol; 6,4- dihydroxy-3-propen chalcone; Dioctyl phthalate; N-methyl-6-β-(1’,3’,5’-trienyl)-3-β-methoxyl-3-β-methyl piperidine; and Dibutyl phthalate have been reported for the first time from the roots of Grewia microcos. Further details Home page URL : http://www.jocpr.com/ For more details PDF Link : http://www.jocpr.com/articles/phytochemical-investigation-of-the-roots-of-grewia-microcos-linn.pdf
Read more

Effect of losartan potassium on the solubility of hydrochlorothiazide by solid dispersion technique

Image
ABSTRACT: The present study was carried out to study the feasibility of a novel drug-drug solid dispersion for improving the dissolution of poorly soluble drugs. Hydrochlorothiazide - losartan potassium, which is a fixed dose combination and used for treatment of hypertension was selected as a model for the study. Hydrochlorothiazide is poorly soluble and its absorption is dissolution rate limited. Losartan potassium is freely soluble and used to effect solid dispersion of hydrochlorothiazide. Solid dispersion of hydrochlorothiazide-losartan potassium (1:4) was prepared by solvent evaporation method and evaluated by FTIR, X-ray diffraction and DSC analyses and in-vitro dissolution characteristics. The data were compared with that of physical mixture of hydrochlorothiazide and losartan potassium and of pure hydrochlorothiazide. The results showed reduction in particle size, change from crystalline form to amorphous form and enhanced the dissolution rate of hydrochlorothiazide from s...
Read more