Journal of Chemical and Pharmaceutical Research

ABSTRACT In the present work, fast dissolving tablets of granisetron HCl were prepared by effervescent method with a view to enhance patient compliance .Croscarmellose sodium is used as a superdisintigrant along with blend of sodium bicarbonate, anhydrous citric acid and tartaric acid in different ratios (as effervescent material)were used and directly compressible mannitol (Pearlitol SD 200) to enhance mouth feel. The prepared batches of tablets were evaluated for hardnss.

ABSTRACT Hemodialysis is a commonly used treatment for renal failure when a kidney has lost its ability to regulate fluids, electrolytes, acid/base balance and toxin removal from the blood. It helps the kidneys to excrete wastes and maintains the electrolyte balance in approximately 90% of end – stage renal disease (ESRD) patients. Albumin consists of one polypeptide chain of 585 amino acids and contains 17 disulfide bonds. Hypoalbuminemia is associated with mortality in patients with ESRD and maintaining optimum albumin levels iscrutial in on hemodialysis (HD).

ABSTRACT Five formulations made from the non-polar extracts of C. retusa have been used as test agents on the flea beetles (P. uniformis). The effectiveness of each formulation (prepared by using Omo detergent solution and petroleum ether) was assessed by the estimation of the number of okro leaf discs (dipped in the respective formulations) eaten by P. uniformis and their mortality within the experimental period. The results of this study have showed that, non-polar constituents of the extract of C. retusa have antifeedant properties onflea beetles since they significantly reduced the feeding of P. uniformis on Okro leaf discs.