Journal of Chemical and Pharmaceutical Research

ABSTRACT : Hystatin is a group of compounds resulted from the derivatization of aaptamine. A series of hystatin 2 derivatives (3, 5-15) have been synthesized and characterized using modern spectroscopic techniques, namely IR, 1H and 13C NMR, UV-Vis and Mass Spectrometer. The synthesized compounds were evaluated for their antibacterial activity against selected bacterial strains of both Gram positive and Gram negative groups, namely Bacillus cereus, Staphylococcus aureus, Micrococcus sp, Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae using standard microbiological protocol of disc-diffusion method. The antibacterial activities of the compounds were assessed by the presence and absence of inhibition zones and minimum inhibition concentration (MIC) values. In general, most of the derivatives showed significant antibacterial activity towards Gram positive bacteria. It was observed that compound 6 exhibited bacterial inhibition activity against all tested bacteria. No...

ABSTRACT: An expeditious and greener one-pot procedure was developed for the synthesis of multisubstituted 2-aminothiophene derivatives. In the presence of catalytic amount of DABCO, ketones or aldehydes, dicyanomethane and elemental sulfur were converted into the corresponding 2-aminothiophene derivatives in moderate to high yields in PEG-200 under sonication. Further details Home page URL : http://www.jocpr.com/ For more details PDF Link:  http://www.jocpr.com/articles/ultrasoundpromoted-synthesis-of-2aminothiophenes-accelerated-by-dabco-utilizing-peg200-as-solvent.pdf

ABSTRACT: The precise causes of psoriasis, a relatively common, chronic, inflammatory and hyperproliferative skin disease, are still not known, thus making it very difficult for treatment. We previously found an in vitro anti-psoriatic activity in ethanolic extract of Annona squamosa L. leaves. Epidermal growth factor receptor (EGFR) and its ligand, transforming growth factor (TGF)-α, have been demonstrated to be strikingly upregulated in active psoriatic plaques, thus implicating their functional roles in psoriatic hyperplasia. The objective of this study was to investigate the molecular effect of ethanolic extract derived from Annona squamosa L. leaves on the EGFR expression using HaCaT keratinocyte cell line as a model. Based on RT-PCR, concentrations at 3.15 and 1.575 µg/mL (IC50= 6.3 µg/mL) significantly reduced the EGFR mRNA expression (P<0.05) as compared to control (HaCaT pretreated with IFN-γ and TNF-α, 10 ng/mL for each) although all three concentrations tested show...

ABSTRACT: The macroalgae showed varied quantities of biochemical constituents like total carbohydrate, total protein and total lipid. Studies were conducted to evaluate biochemical composition of Spatoglossum asperum. Fatty acid, vitamins and minerals composition were carried out by using gas chromatography method and flame atomic absorption spectrophotometry method respectively. Among biochemical content total protein is present in high amount, 11.03 ± 0.06%, total carbohydrates is 6.55 ± 0.14% and total lipid is 3.14± 0.14%. Among the 7 identified fatt y acid, Linoleic acid (29.41± 0.01%) and stearic acid (21.9 9 ± 0.01%) are found to be the major components. Among vitamins, vitamin C (15.60 ± 0.00 mg/100gm) and Nia cin (10.86 ± 0.02 mg/100gm) are present in major qu antities. Macro minerals such as Potassium (203.38 ± 0.02 mg/ 100gm), Sodium (145.50 ± 0.10 mg/100gm) and Calcium (134.51 ± 0.01mg/100gm) were identified in higher amount. Further details Home page URL : http:...

ABSTRACT: Maintaining some chlorine residual concentration in the water distribution system is the key step to the safety of water quality. In this text, it puts forward a new chlorine decay model after studying the chlorine spatial and temporal decay. Each decay coefficient to the model adopts the dynamic simulation of the computer to estimate. Also a modeling case is presented, it shows that the new model is more practicality and adaptability. On the basic of the water quality model, it builds the early-warning and prediction system, which will have great realistic meanings for improving the water quality and ensuring the safety of the water supply system. Further details Home page URL : http://www.jocpr.com/ For more details PDF Link:   http://www.jocpr.com/articles/study-on-the-chlorine-decay-model-in-the-water-distribution-system.pdf

ABSTRACT: In the present investigation silver nanoparticles of spherical shape was synthesized biologically by rapid biological drip method using marine brown macro algae, Sargassum wightii (S. Wightii). Seaweed extract act as a reducing agent for silver nitrate. Silver nanoparticles have been characterized by UV-Visible spectrophotometer, FourierTransform Infrared spectroscopy (FTIR), X-ray diffractometer (XRD) and High Resolution Transmission Electron Microscope (HR-TEM). Antibacterial activity of these nanoparticles was carried out by antibiotic disc diffusion method against pathogenic microorganisms such as Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella pneumoniae. Seaweed S. wightii mediated silver nanoparticles were found to be effective against these pathogens than silver nitrate. Further details Home page URL : http://www.jocpr.com/ For more details PDF Link: http://www.jocpr.com/articles/enhanced-bactericidal-effect-of-silver-n...

ABSTRACT: In recent years regulation of the enzymatic activity of tyrosinase has been the main focus of investigation due to its potential applications in medicine, agriculture and cosmetics. In the present study, we evaluated its docking behaviour of nine different ligands (such as Coenzyme Q10, L-DOPA, Embelin, Idebenone, Kojic acid, 5-Methyl embelin, Potassium embelate, L-Tyrosine and Vilangin)with the copper-bound Streptomyces castaneoglobisporus tyrosinase & Agaricus bisporus (Mushroom tyrosinase). Autodock 4.0 tool was used to investigate its putative binding residues. Molecular physicochemical and the drug-likeness studies reveal that L-DOPA, Kojic acid and LTyrosine complies very well with thumb rule of five. With regard to affinity and binding energy calculationswith the targeted protein (Streptomyces castaneoglobisporus tyrosinase), kojic acid showed least affinity value -3.52 kcal/mol, compared to other chosen ligands. Similarly, in case of Agaricus bisporus (Mush...

ABSTRACT: With China tops global patent filings, Chinese innovation capability is coming in to the picture. However, is this real innovation capability of China? This paper calculates and analyzes the Annual Growth Rate of R&D inputs and outputs from Scientific Research and Development Institute (SRDI) in PR. China, covering the time period of 1999-2010. pointing out the existing questions and reasons. And then assesses the R&D efficiency of SRDI by using Data Envelopment Analysis (DEA) method. The main contribution of this paper is that the activities of SRDI are analyzed from different perspectives and concludes that the total innovation capability of SRDI in China is exciting but the quality of outputs needs to be improved further in the future. Further details Home page URL : http://www.jocpr.com/ For more details PDF Link:  http://www.jocpr.com/articles/rd-growth-and-efficiency-of-scientific-research-development-institutes-in-china.pdf

ABSTRACT: Adsorption is a process that occurs when a gas or liquid solute accumulates on the surface of a solid or, more rarely, a liquid (adsorbent), forming a molecular or atomic film (the adsorbate). Exchange adsorption, Physical adsorption and chemical adsorption have been recognized as adsorption types. This study involves the separation of an azeotropic mixture (benzene-cyclohexane) by adsorption technique using Eu-GAC(Granular Activated Carbon) and Sand. The Eu-GAC was produced by thermal pyrolysis of Eucalyptus tree branches and leaves and the Sand was collected from El-Khums seaside. The influence of several parameters such as dose or mass of adsorbent, pH, mesh number and contact time were investigated. The optimum adsorption efficiency occurred at pH 3. The optimum contact time for both adsorbents was found to be 3 hours. The adsorption of azeotropic mixture (benzenecyclohexane) improved by increasing adsorbent dose and mesh number (Mesh No 100). This study has conclu...

ABSTRACT: Ontology similarity calculation and ontology mapping are crucial research topics in information retrieval. Ontology, as a concept structure model, is widely used in biology, physics, geography and social sciences. In this paper, we present new algorithms for ontology similarity measurement and ontology mapping using harmonic analysis and diffusion regularization on hypergraph. The optimal function gets from new algorithms manifests good smoothness and well reflects the structure of the ontology graph. Two experimental results show that the proposed new technologies have high accuracy and efficiency on ontology similarity calculation and ontology mapping in certain applications. Further details Home page URL : http://www.jocpr.com/ For more details PDF Link:  http://www.jocpr.com/articles/diffusion-and-harmonic-analysis-on-hypergraph-and-application-in-ontology-similarity-measure-and-ontology-mapping.pdf

ABSTRACT: Schiff base synthesis of pyrazolone derivatives containing Indole moiety bearing-4-oxazetiding ring were synthesized by the condensation of 2-(3-(3chloro -1-(4-substitued phenyl )-4-oxozetiding -2-yl(1H-Indole –yl Aceto hydrazone with ethyl 2-(2-(4-substitued phenyl hydrazone)(-4,-4,-4 tri frouro-3-oxo butanoate) this reaction was subjected in schiff base reaction .The structure of these newly synthesized compounds were characterized by 1H NMR,13CNMR ,Mass ,IR, and elemental analysis. Further details Home page URL : http://www.jocpr.com/ For more details PDF Link: http://www.jocpr.com/articles/synthesis-characterization-and-antiinflammatory-activity-of-indole-derivatives-bearing4oxazetidinone.pdf

ABSTRACT: As a high-tech industry, the pharmaceutical industry in China is uncompetitive and is difficult to go further. By evaluating the innovating capability of different pharmaceutical companies, this paper attempts to find the key factors affecting the innovating ability and provides suggestions for pharmaceutical companies to improve the innovating capability. The research indicates: Independent innovating factor and policy-influencing factor are two factors and the key factors affecting the innovating capacity of different pharmaceutical companies are different; the ability of independent innovation is the key influencing factors to the state-owned pharmaceutical companies, while policy- influencing factor plays a key role in foreign-invested pharmaceutical companies. For more details PDF Link: http://www.jocpr.com/articles/analysis-on-innovation-capability-and-influencing-factors-in-chinese-pharmaceutical-industry.pdf Further details Home page URL : http://www.j...

ABSTRACT: Smartongue is a voltammetric electronic tongue, based on a non-specific sensors array and one special voltammetry, so called multi-frequency large amplitude pulse voltammetry (MLAPV), which made its responding signals have much overlapping information. Three non-linear multivariate data analysis methods, Kernel principal component analysis (Kernel PCA), Locally linear Embedding (LLE) and Sammon mapping, were used to dig the information from the collecting data of Smartongue. One linear data analysis method, normal principal component analysis (PCA) and the discrimination index (DI value) were applied as the reference method and as the quantitative indicator to evaluate the discrimination ability. The results indicated that three non-linear data processing methods exhibited much more feasible and efficient than PCA in Smartongue. Sammon mapping is the most suitable non-linear method to process data in Smartongue. It was able to extract the useful information from the raw ...

ABSTRACT: In the face of global competition, the requirement for dimensional accuracy, mechanical properties and surface properties has become a major challenge on aluminum manufacturing industries. Conventional rolling force formulas, however, provide not more than reasonably exact approximations. The mathematical modeling of the hot rolling process has long been recognized to be a desirable approach to aid in rolling operating practice and the design of mill equipment to improve productivity and quality. However, many factors make the theoretical analysis of the rolling process very complex and time-consuming. This paper presents a prediction method based on the Artificial Bee Colony algorithm and BP neural network, which was developed in order to improve the prediction of rolling force in hot strip rolling process. The architecture of BP neural network is optimized by Artificial Bee Colony algorithm. Comparing with the Sims mathematical model and BP neural network, the experi...

ABSTRACT: A UV- Spectrophotometric method has been developed for the determination of Gatifloxacin and Flurbiprofen Sodium in their pharmaceutical formulation on measurement of absorbance at two maximum Gatifloxacin respectively. The method was validated for various parame regression analysis data for the calibration plots showed good linear relationship 18 µg/ml and 0.6 – 1.8 µg/ml and correlation co Flurbiprofen Sodium respectively. Further details Home Page URL :   http://www.jocpr.com/ For more details PDF Link:  http://www.jocpr.com/articles/simultaneous-estimation-of-gatifloxacin-and-flurbiprofen-sodium-in-ophthalmic-formulation-by-uv-specrophotometric-method.pdf   

ABSTRACT: Chitinase is produced by a number of organisms and it is one of the most important enzymes with industrial significance. In this study, we describe the optimization of medium composition with increased production of chitinase for Serratia marcescens strain JPP1. The strain was isolated from the peanut hulls in Jiangsu Province, China and exhibited antagonistic activity against aflatoxins and chitinolytic activity by producing chitinases. Medium composition was optimized using statistical experimental design: Plackett-Burman design was applied to find the key ingredients, and the five significant variables were peptone, glucose, ammonium sulfate, fructose and beef extract. Further details Home Page URL :   http://www.jocpr.com/ For more details PDF Link:  http://www.jocpr.com/articles/optimization-of-nutrients-for-chitinase-production-by-serratia-marcescens-jpp1-against-aflatoxin-using-statistical-exper.pdf

ABSTRACT: This research was undertaken to assess the in vitro antifungal potential of the essential oils of clove, cinnamon, aniseed, green prickleyash, Pricklyash peel, cumin and fennel against the five major fungal pathogens of fruits and vegetables using the method of inhibitory zone, the inhibition to the mycelial growth and the minimal inhibitory concentration.i.e, Penicillium italicum, penicillium expansum, Monilinia fructigena ， Penicillium sp. and Fusarium spp. The results indicated that clove had significant antifungal activity to all strains, especially against Penicillium italicum. Cinnamon and aniseed had strong antifungal activity to all strains tested except Fusarium spp. ， especially against Monilinia fructigena. Moreover, Clove could inhibit mycelial growth of all pathogens completely and the minimal inhibitory concentration of clove was less than or equal to 0.5% (v/v). The present results demonstrated that clove oil could be potential sources of natural fungicide...

ABSTRACT: As compulsory courses, the ideological and political courses of instates of higher learning can strengthen the moral integrity and political awareness. They are also the main method of moral education in institutes of higher learning. Ideological and political courses can improve the comprehensive development of college students and enable college students to become eligible successors and constructors of socialism. Nowadays, well-rounded talents are badly needed and social adaptation ability is an essential factor in students’ competence in labor market. Ideological and political courses, however, can provide students with right guidance and improve students’ capability in social activity and the capacity to resist setbacks. In this way, the students can better adapt to the society. Further details Home Page URL :   http://www.jocpr.com/ For more details PDF Link:  http://www.jocpr.com/articles/improving-college-students-social-adaptation-ability-th...

ABSTRACT: Floating matrix tablets of clarithromycin were developed to prolonged gastric residence time and thereby increase drug availability. The tablets were formulated by wet granulation technique, using polymers such as Guar Gum, HPMC-K15M and HPMC-K100M, and other standard excipient. Tablets were evaluated for physical characteristics viz, hardness, percentage friability, floating capacity, weight variation and content uniformity. Further, tablets were evaluated for in-vitro release characteristics for 12hr. Increasing the polymer ratio the FLT was increase but the drug release was decreased. Further details Home Page URL :   http://www.jocpr.com/ For more details PDF Link:  http://www.jocpr.com/articles/formulation-and-evaluation-of-clarithromycin-gastroretentive-dosage-form.pdf

ABSTRACT: The inhibition of the corrosion of steel in 1 M HCl by pyrazole compounds 5-bromo-N-((3,5-dimethyl-1H-pyrazol-1- yl)pyridine-2-amine (AB8) and 3,5-dibromo-N-((3,5-dimethyl-1H-pyrazol-1-yl)pyridine-2-amine (AB9) has been studied by weight loss, electrochemical polarisation and electrochemical impedance spectroscopy measurements. The results obtained reveal that these compounds are efficient inhibitors. The inhibition efficiency increases with the increase of inhibitor concentration and reached 95 % for AB9 at 10-3 M. Potentiodynamic polarisation studies clearly reveal that the presence of all inhibitors does not change the mechanism of hydrogen evolution and that they act mixed inhibitors. The temperature effect on the corrosion behaviour of steel in 1 M HCl without and with the inhibitors at 10-3M was studied in the temperature range from 308-333K, it allows to determine the several thermodynamic parameters.  The inhibitors were adsorbed on the steel surface ...

ABSTRACT: Disodium octoborate tetrahydrate (DOT), boric acid (BA), magnesium sulfate (MgSO4) and fire retardant DBM were selected as the main ingredients to develop a fire retardant for Southern Pine. A Thermo Gravimetric Analyzer was used to evaluate the temperature effects of Southern Pine samples treated with the DBM. The results showed that Boron-Containing fire-retardant improved Southern Pine fire retardant performance, the mass loss rate decreased, the char yield and the peak temperature of maximum mass loss increased. Thermokinetic method was used to analyze the TG curves of the treated wood, so as to illustrate the DBM treating agent’ mechanism of flame retardant effect on wood, In order to illustrate the activation energy in different combustion stages with quantity, the TG curves were further analyzed by thermokinetic method to obtain thermokinetic parameters of different phases during wood pyrolysis. Further details Home Page URL :   http://www.jocpr.com/...

ABSTRACT: Terahertz filters with dual-band and sharp slope rate of edge characteristics are reported. We realize the change from single band to dual-band by adding a SRR to the original structure. The mechanism for the dual-band is attributed to introducing a new resonance point. The slope rates of edges for two stop-bands are 297dB/THz, 297 dB/THz, 287 dB/THz, and 354 dB/THz. Tuning bandwidths and center frequencies can be realized by modulating the main parameters of the structure. Besides, the filter is insensitive to the polarization of the THz radiation under g=0 m m. Further details Home Page URL :   http://www.jocpr.com/ For more details PDF Link:  http://www.jocpr.com/articles/dualband-terahertz-filters-with-sharp-slope-rate-of-edge-based-on-twolayered-composite-metamaterial.pdf

ABSTRACT: Dyeing wastewater has caused serious synthetic dyes pollution on both water bodies and soil in China. This study investigated the mechanism of azo dye removal by different vegetative organs of hydroponically grown sunflowers. In all treatments, the percent of dye removal by living organs was higher than corresponding dead organs. The results show that decolorization of Evans blue by tissues of sunflowers was partly attribute to degradation and partly due to sorption. Moreover, the biodegradtion played a greater role than sorption in the dye removal. The biodegradation rate of the dye was estimated. Realistic values of Km and Vmax were estimated by a computer program using non-linear regression treatment and Lineweaver–Burk model. In both methods, the rate of azo dye removal from the aqueous solution by roots was the highest, followed by leaves and stems. Further details Home Page URL :   http://www.jocpr.com/    For more details PDF Link:...

ABSTRACT: With the rapid development of network communication and broad application of multimedia technology, copyright protection of digital media work is becoming more and more important. Digital watermarking is viewed as an effective tool for copyright protection of multimedia data. At first the princip1e, research background and status of digital watermark is described. Then, a blind watermarking algorithm based on DWT is proposed. The watermark image is scrambled by a generalized Arnold transform so as to improve the security of the watermark; the watermark is embedded into the middle-frequency subband which guarantees the robustness of the algorithm; In order to implement the blind extraction, this paper improves an embedding algorithm based on HVS, which enhances the applicability of the algorithm. This paper tests the algorithm by VC++6.0, and quantity of experiment data shows that algorithm has good robustness, and the imperceptibility of watermark can be guaranteed at ...

ABSTRACT:   Extrapyramidal movement disorders are major neurodegenerative disorders caused due to dopamine deficiency in the basal ganglia. It may be caused due to oxidative stress producing free radicals that destroys dopamine producing neurons. Catalepsy, Tardive dyskinesia etc are the symptoms of certain nervous disorders such as Parkinson’s disease & epilepsy in animal models. Phytochemical analysis of Eclipta alba (Bhringaraj) shows that it contains urosolic acid having antioxidant properties. The present study was undertaken to evaluate the possible protective effect of Eclipta alba leaf extract (EALE) on oxidative stress & haloperidol induced extrapyramidal symptoms. Male wistar albino rats (150-200gms) were used for the experiments. Catalepsy was induced with haloperidol (1mg/kg IP) using block method & was measured by standard procedure of Zazpe etal 2006.  Effect of EALE in a dose of 100,200,400mg/kg on haloperidol induced catalepsy &vacu...

  ABSTRACT : Because of the scarcity of water resources and serious environment, it becomes much more emergence to develop the water saving agriculture. Drip irrigation and straw mulch both at home and abroad were wide studied. However, How to utilize saline water reasonably, scientificly, efficiently and safely has always been a core problem in farmland irrigation using saline water. Based on the relative research about salinity water irrigation, this paper studied on the effect of different salinity water irrigation and soil salt contents on maize growth in a plastic bucket experiment in Yonggu village, Ningxia shizuishan city of Ningxia located in Yellow River Irrigation district. The main results are as follows, showed that the salinity water had much greater effect on maize emergence rate than that of soil initial salt content. With the increase of irrigation water salinity and soil initial salt content, the maize height all decreased. Under the same soil saline content, ...

  ABSTRACT : The effect of some prepared cefepime metal complexes with Cr(III), Mn(II), Fe(III), Co(II), Cu(II), Zn(II), Cd(II), Hg(II) and mixed metals (Fe,Ni) or (Cu,Fe) on the activity and kinetics of purified acetyl cholinesterase (AChE) and monoamine oxidase (MAO-B&A) were investigated. The brain AChE and MAO-A & B from Egyptian Mediterranean buffalo (Bas Buballus) was purified by ammonium sulphate precipitation, Sephadex G-25, and Sephadex G-100. The effect of these prepared metallo cefepime on the activity of pure AChE and also (MAO-B&A) were carried out in vitro by using standard colorimetric assays. The results revealed that AChE was inhibited by Mn(II) ,Cu(II) with different molar ratios(Cu:Cefepime) [(1:3)&(4:1)] ,Zn(II) and mixed metal [Fe(III),Ni(II)] cefepime complexes. Among the target compounds, Mn-cefepime complex showed the highest inhibitory activity 66.6% towards AChE with IC50 945µM.  The Lineweaver–Burk plot of the inhibition ...

  ABSTRACT : Enlightened by Lota’s report, this paper first analyzes the volatile oil chemotype of Citrus reticulata Blanco peel from different cultivars according to the contents of four compounds such as Limonene, γ-Terpinene, Linalool, and Benzoic acid, 2-(methylamino)-, methyl ester (or called Methyl methanthranilate).In fact, all oils have Limonene as a primary component, and they all can be classified as the chemotype of Limonene. And most oils comprise γ-Terpinene as the second high amount component, some oils comprise the characteristic components as Linalool and Methyl methanthranilate. Then, based on the standard that ifγ-Terpinene≥ 9.0%, Linalool ≥ 4.0%, Methyl methanthranilate≥ 1.0%,the oil can be continually sub classified as the chemotype of γ-Terpinene, Linalool,orMethyl methanthranilate. Following this principle, the oilchemotype of different cultivars in dissimilar area presents somesimilarities and differences.     Further details Home Page ...

  ABSTRACT : Dielectric properties of alcohol-water mixtures were measured at the selected microwave frequency by a sensitive sensor method using a network analyzer. The effects of concentration in terms of molar fractions on dielectric properties were investigated. Further details Home Page URL: http://www.jocpr.com/ For more details PDF Link:  http://www.jocpr.com/articles/effective-permittivity-of-alcohol--water-mixtures-as-influenced-by-concentration.pdf

  ABSTRACT : The present study was conducted to document the ethnomedicinal knowledge of two cultural communities residing in Kanyakumari district, Tamilnadu, South India. Ethnobotanical uses of medicinal plants were obtained through intensive structured and semi-structured interviews from traditional medicinal practitioners (TMP) and elders of the community. The plant specimens were identified by using the herbarium specimens available in the Department of Botany, Nesamony Memorial Christian College, Marthandam. A total of 131 plant species has been used to treat various ailments among the two cultural communities of Kanyakumari district. Regarding the medicinal uses of plants species it varies among the community, whereas few plants have same usage. In the present survey some medicinal plants have been reported for the first time in the study area. The use of plants among the two cultural communities reflects their knowledge in ethnomedicine and further investigation on thes...

  ABSTRACT : The paper proposed a method that endogenous two-sided network effects were proved in transaction services that the value of services to suppliers (buyers)increases with increasing number of buyers (suppliers) while decreases with increasing number of suppliers (buyers). Network led to the development pace of people’s lives; promote the development of online shopping and the rise of third-party payment platform. For more benefits, the platform owner must aim at transaction services of staple commodities with high price elasticity and large quantities of market supply and demand, while reducing the marginal usage costs of buyers and suppliers with effective measures. Further details Home Page URL: http://www.jocpr.com/ For more details PDF Link:  http://www.jocpr.com/articles/ecommerce-model-and-platform-based-on-the-thirdparty.pdf

  ABSTRACT : Herbs have been used as traditional medicine for centuries and believed to possess antioxidant properties. We screen aqueous extracts from 40 medicinal plants in Thai traditional medicine that believed to reduce the risks of cardiovascular diseases, diabetes and cancers. Total antioxidant activity was measured by Trolox equivalent antioxidant capacity (TEAC) assay. In the plants associated with the treatment of cardiovascular diseases, we found that the total antioxidant activities of Nelumbo nucifera Gaertn., Bixaorellane, Michelia alba, Mammea siamensis, and Michelia champaca were higher than others. In the plants associated with the treatment of diabetes, we found that total antioxidant activities of Xylinbaria minutiflora, Leptocarpus disjuntus, Salacia chinensis, Albizia myriophylla and Urceola minutiflora were higher than others. In the plants associated with the treatment of cancers, we found that total antioxidant activities of Balanophora abbreviata, Alpi...

  ABSTRACT : In the process of practicing Taijiquan, the symptom of knee pain will happen from time to time, the pain symptom is closely connected to such factors as the movement postures, technical movements, contraction force of lower limb muscles and ligament traction. This research is designed to analyze and compare the sports biomechanics between the trainees with the symptom of knee pain and Taijiquan coaches with skilled technology through the experimental method; the results show that the result of knee pain symptom has something to do with the unscientific training and failing to master the correct technical essentials. Further details Home Page URL: http://www.jocpr.com/ For more details PDF Link:  http://www.jocpr.com/articles/analysis-on-biomechanics-characteristics-and-countermeasures-for-knee-pain-when-practicing-taijiquan.pdf   

  ABSTRACT : Process parameters on enzymatic hydrolysis and molecular weight distribution of human-like collagen （ HLC ） hydrolysates were investigated. HLC was hydrolysed by trypsin and pepsin, the optimal process parameters were obtained by the single-factor and orthogonal experiments. The molecular weight distribution of hydrolysates (MW) was determined using both SDS-PAGE and Sephadex G25 partition. In the study, the maximum degree of hydrolysis (DH) of HLC hydrolysate obtained by trypsin (temperature 50°C, pH 8.0, HLC concentration 15mg/mL, E/S=80%, 8 h) was 70.9%, MW ranged from 500 to 1 400 Da. While that obtained by the pepsin (temperature 50° C, pH 2.5, HLC concentration=5mg/mL, and E/S=3%, 7 h) was 24.25%, MW ranged from 4000 to 6500 Da. Further details Home Page URL: http://www.jocpr.com/ For more details PDF Link:  http://www.jocpr.com/articles/enzymatic-hydrolysis-of-humanlike-collagen-and-molecular-weight-distribution-of-hydrolysates.pdf

  ABSTRACT : In this paper, by using new linearization method we present an optimization algorithm for globally solving a class of multiplicative problems which have a broad application in computational chemistry, information technology, and so on. By utilizing characteristic of quadratic function, a series of linear relaxation programming problem of the initial problem can be derived and which can provide a reliable lower bound. By means of the subsequent solutions of a sequence of linear relaxation programming problems, the proposed optimization algorithm converges to the global optimal solution of the initial problem. Numerical experimental results show that the proposed algorithm is feasible and effective. Further details Home Page URL: http://www.jocpr.com/ For more details PDF Link:  http://www.jocpr.com/articles/an-optimization-algorithm-for-solving-a-class-of-multiplicative-problems.pdf

  ABSTRACT : In this study, with the use of LF-NMR technology, IR pulse sequence and CPMG pulse sequence were applied to detect the changes in the moisture of fresh milk samples, which were stored up at 30°C for 96 hours. Relaxation time signal T1 and T2 were measured to analyze synthetically the combination and mobility of water molecules. Furthermore, T21,T22 proton density were inversed by T2 to observe the change of bound water and free water, then the total water content can be determined by superposition of inversion signals. Meanwhile, the ratio of T21 and T22 can be used for quality control and rapid detection of corruption. The experiment results demonstrate that the moisture of milk can be used to determine the quality variation of milk. This research method analyzes and summarizes the change rules of moisture combination state in fresh milk during storage. Consequently, the freshness of milk can be determined rapidly and effectively, and the results will be benefici...

  ABSTRACT : The kindergarten teachers' overall quality evaluation index system including three first grade indexes involves professional concept and ethics, professional knowledge, professional ability, nine second grade indexes and twenty-six third grade indexes. This paper uses Delphi technique, AHP method and unweighted pair group method to count the weight of the kindergarten teachers' comprehensive evaluation index. Further details Home Page URL: http://www.jocpr.com/ For more details PDF Link:  http://www.jocpr.com/articles/using-delphi-method-and-ahp-for-the-research-on-kindergarten-teachers-comprehensive-quality-evaluation-index-weight.pdf

  ABSTRACT : In recent years, bioplastics are becoming increasingly prominent owing mainly to scarcity of oil, increase in the cost of petroleum-based commodities, and growing environmental concerns with the dumping of non-biodegradable plastics in landfills. In the present paper, we first discuss the definition and basic facts as well as the major advantages of bioplastics, then the main differences between plastics and bioplastics in packaging are briefly reviewed. Finally, possible future developments of bioplastics are prospected. Further details Home Page URL: http://www.jocpr.com/ For more details PDF Link:  http://www.jocpr.com/articles/bioplastics-and-their-role-in-achieving-global-sustainability.pdf

  ABSTRACT : Currently, search of new plant compounds possessing anticancer and antioxidant activity is a vital area of research in plant medicine, as plant products are safe and relatively low of cost. Berberine, an isoquinoline alkaloid derived from plants, is a traditional medicine for many diseases in India. In recent times, berberine has been revealed to have potent anticancer activity against various cancers. Information regarding the effect of berberine on experimental lung cancer is limited. The objective of the present study to evaluate the antioxidant potential of berberine on experimental lung carcinogenesis. Thirty Swiss albino mice were divided into five groups of six animals each. Animals in group I received corn oil orally and served as control. Group II were administered with 50 mg/kg b.wt. of benzo(a)pyrene (B(a)P) twice a week for 4 consecutive weeks to induce lung cancer by the end of 16th week. Group III received 50 mg/kg b.wt. berberine on alternate days...